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Article in Japanese
Abstract
Case Report
A case of drug-induced lung injury caused by eltrombopag
Yuya Inadaa Tomoyoshi Itoha Kohei Iwasakia,b Ryo Mizutania Masato Shinokia Kanako Tamuraa
aDepartment of Respiratory Medicine, Kansai Electric Power Hospital
bIwasaki Clinic Internal and Pulmonary Medicine
ABSTRACT
A 70-year-old woman was administered prednisolone and eltrombopag after being diagnosed with eosinophilia and idiopathic thrombocytopenic purpura 14 months ago. Prednisolone was discontinued 6 months ago, and the patient started to develop cough and dyspnea 2 months ago. Computed tomography scans revealed infiltrative opacities in both lungs, and transbronchial lung biopsy findings revealed organizing pneumonia. The symptoms and infiltrative opacities improved only after the discontinuation of eltrombopag. Accordingly, the patient was diagnosed with drug-induced lung injury caused by eltrombopag. It is therefore necessary to consider the risk of the development of drug-induced lung injury when administering eltrombopag.
KEYWORDS
Eltrombopag Thrombopoietin receptor agonist (TPO-RA) Drug-induced lung injury
Received 20 Jan 2023 ／ Accepted 20 Apr 2023
AJRS, 12(4): 191-195, 2023
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