*Seiji Niho¹・Hiroshige Yoshioka²・Satoshi Watanabe³・Hiroshi Sakai⁴・Katsuyuki Hotta⁵・Mitsuhiro Takenoyama⁶・Kazuhiko Yamada⁷・Shunichi Sugawara⁸・Yuichi Takiguchi⁹・Yukio Hosomi¹⁰・Keisuke Tomii¹¹・Nobuyuki Yamamoto¹²・Makoto Nishio¹³・Yuichiro Ohe¹⁴・Ami Kamada¹⁵・Kazumi Suzukawa¹⁵・Yukie Omori¹⁵・Sotaro Enatsu¹⁵・Kazuhiko Nakagawa¹⁶・Tomohide Tamura¹⁷
Department of Thoracic Oncology, National Cancer Center Hospital East¹；Kurashiki Central Hospital²；Graduate School of Medical and Dental Sciences, Niigata University³；Saitama Cancer Center⁴；Okayama University Hospital⁵；National Hospital Organization Kyushu Cancer Center⁶；Kurume University School of Medicine⁷；Department of Pulmonary Medicine, Sendai Kousei Hospital⁸；Graduate School of Medicine, Chiba University⁹；Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital¹⁰；Department of Respiratory Medicine, Kobe City Medical Center General Hospital¹¹；Third Department of Internal Medicine, Wakayama Medical University¹²；The Cancer Institute Hospital of Japanese Foundation for Cancer Research¹³；National Cancer Center Hospital¹⁴；Eli Lilly Japan K.K.¹⁵；Department of Medical Oncology, Kindai University Faculty of Medicine¹⁶；St. Luke's International Hospital¹⁷

*原田大二郎¹・宇田川　響²・杉山　栄里³・原田　敏之⁴・安宅　信二⁵・小山　　良⁶・渡部　　聡⁷・中村有希子⁸・畑地　　治⁹・田中　文啓¹⁰・新実　彰男¹¹・木田　　博¹²・里内美弥子¹³・山中　竹春¹⁴・後藤　功一²
四国がんセンター呼吸器内科¹；国立がん研究センター東病院呼吸器内科²；国立がん研究センター先端医療開発センター³；JCHO北海道病院呼吸器内科⁴；近畿中央胸部疾患センター内科⁵；順天堂大学順天堂医院呼吸器内科⁶；新潟大学医歯学総合病院呼吸器・感染症内科⁷；横浜市立市民病院呼吸器内科⁸；松阪市民病院呼吸器センター⁹；産業医科大学病院第2外科¹⁰；名古屋市立大学呼吸器・アレルギー内科¹¹；大阪大学医学部呼吸器内科¹²；兵庫県立がんセンター呼吸器内科¹³；横浜市立大学大学院医学研究科臨床統計学¹⁴

*Kaoru Kubota¹・Johan F. Vansteenkiste²・Jarushka Naidoo³・Corinne Faivre-Finn⁴・Mustafa Özgüroğlu⁵・Augusto Villegas⁶・Davey Daniel⁷・Shuji Murakami⁸・Rina Hui⁹・Ki Hyeong Lee¹⁰・Byoung Chul Cho¹¹・Lynne Poole¹²・Catherine Wadsworth¹³・Phillip A. Dennis¹⁴・Scott J. Antonia¹⁵
Nippon Medical School Hospital, Japan¹；University Hospitals KU Leuven, Leuven, Belgium²；Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA³；The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK⁴；Istanbul University Cerrahpasa School of Medicine, Istanbul, Turkey⁵；Cancer Specialists of North Florida, Jacksonville, FL, USA⁶；Tennessee Oncology, Chattanooga, TN, and Sarah Cannon Research Institute, Nashville, TN, USA⁷；Kanagawa Cancer Center, Yokohama, Japan⁸；Westmead Hospital and the University of Sydney, Sydney, NSW, Australia⁹；Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, South Korea¹⁰；Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea¹¹；AstraZeneca, Cambridge, UK¹²；AstraZeneca, Alderley Park, UK¹³；AstraZeneca, Gaithersburg, MD, USA¹⁴；H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA¹⁵

*Hiroyuki Suzuki¹・Noriyuki Ebi²・Alyssa B. Klein³・Sang-We Kim⁴・Zhang Li⁵・Yuki Owada-Ozaki¹・Alix Berton³・Norah Shire³・Tapashi Dalvi³・Anne-Marie Boothman³・Abdelouahid Tajar⁶・Coralie Lecomte⁶
Fukushima Med University Hosp¹；Aso Co., Ltd Iizuka Hosp²；AstraZeneca³；Asan Medical Centre⁴；Sun Yat-sen University Cancer Center⁵；IQVIA⁶

*岩井　俊樹・杉本　正道・脇田　大功・山本　　要
中外製薬株式会社プロダクトリサーチ部

*David A. Schaer・Ruslan D. Novosiadly・Nelusha Amaladas・Erik Rasmussen・Zhao Hai Lu・Andreas Sonyi・Carmine Carpenito・Yanxia Li・Shuang Luo・Andrew Capen・Catalina M. Meyer・Xiaodong Huang・Jason Manro・Gregory P. Donoho・Thompson Doman・Gerald Hall・Sandaruwan Geeganage・Michael Kalos
Lilly Research Laboratories, Eli Lilly and Company, USA

*Kazuhiko Nakagawa¹・Helen Brown²・Johan Vansteenkiste³・Manuel Cobo⁴・Tom John⁵・Craig Barker²・Alexander Kohlmann⁶・Alexander Todd⁷・Matilde Saggese⁷・Juliann Chmielecki⁸・Aleksandra Markovets⁹・Suresh S. Ramalingam¹⁰
Department of Medical Oncology, Kindai University School of Medicine, Osaka, Japan¹；Precision Medicine Laboratories, Precision Medicine and Genomics, IMED Biotech Unit, AstraZeneca, Cambridge, UK²；Respiratory Oncology Unit（Respiratory Diseases）, University Hospital KU Leuven, Leuven, Belgium³；Medical Oncology Department, University Regional Hospital of Málaga, IBIMA, Malaga, Spain⁴；Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Victoria, Australia⁵；Oncology Companion Diagnostics Unit, Precision Medicine and Genomics, IMED Biotech Unit, AstraZeneca, Cambridge, UK⁶；Global Medicines Development, Biometrics and Information Sciences, AstraZeneca, Cambridge, UK⁷；Translational Sciences, IMED Biotech Unit, AstraZeneca, Waltham, MA, USA⁸；Bioscience, IMED Biotech Unit, AstraZeneca, Waltham, MA, USA⁹；Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA, USA¹⁰

*甲原　雄平^1,2・長友　　泉¹・小山　正平¹・平田　陽彦¹・木島　貴志³・木田　　博¹
大阪大学医学部附属病院呼吸器免疫内科¹；日本生命病院総合内科²；兵庫医科大学呼吸器内科³

*Makoto Nishio¹・Jong S. Lee²
The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Japan¹；Seoul National University Bundang Hospital, Seoul, South Korea²

*Tony Mok¹・Shun Lu²・Yi-Long Wu³
The Chinese University of Hong Kong, Hong Kong¹；Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai JiaoTong University, Shanghai, China²；Guangdong Lung Cancer Institute, Guangdong General Hospital ＆ Guangdong Academy of Medical Sciences, Guangzhou, China³

*Fumio Imamura¹・Ying Cheng²・Caicun Zhou³・Yuichiro Ohe⁴・Byoung Chul Cho⁵・Meng-Chih Lin⁶・Margarita Majem⁷・Riyaz Shah⁸・Yuri Rukazenkov⁹・Alexander Todd¹⁰・Aleksandra Markovets¹¹・Carl Barrett¹¹・Juliann Chmielecki¹¹・Jhanelle E. Gray¹²・Suresh S. Ramalingam¹³
Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan¹；Jilin Provincial Cancer Hospital, Changchun, China²；Department of Oncology, Pulmonary Hospital of Tongji University, Shanghai, China³；Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan⁴；Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea⁵；Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan⁶；Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain⁷；Kent Oncology Centre, Maidstone Hospital, Maidstone and Tunbridge Wells NHS Trust, Maidstone, UK⁸；Global Medicines Development, GMED Oncology, AstraZeneca, Cambridge, UK⁹；Biometrics and Information Sciences, AstraZeneca, Cambridge, UK¹⁰；Translational Sciences, IMED Biotech Unit, AstraZeneca, Waltham, MA, USA¹¹；Department of Thoracic Oncology, H. Lee Moffitt Cancer Center ＆ Research Institute, Tampa, FL, USA¹²；Winship Cancer Institute, Emory University, Atlanta, GA, USA¹³

*Shuji Murakami¹・Takayasu Kurata²・Takaaki Tokito³・Kaoru Kubota⁴・Shunichi Sugawara⁵・Manabu Hayama⁶・Phillip Dennis⁷・Catherine Wadsworth⁸・Maria Taboada⁹・Scott J Antonia¹⁰
Kanagawa Cancer Center, Japan¹；Kansai Medical University Hospital, Hirakata, Japan²；Kurume University Hospital, Kuruma, Japan³；Nippon Medical School Hospital, Tokyo, Japan⁴；Sendai Kouseikai Hospital, Sendai, Japan⁵；AstraZeneca K.K., Osaka, Japan⁶；AstraZeneca, Gaithersburg, MD, USA⁷；AstraZeneca, Alderley Park, UK⁸；AstraZeneca, Cambridge, UK⁹；H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA¹⁰