*Takayasu Kurata¹・Shirish M. Gadgeel²・Delvys Rodriguez-Abreu³・Balazs Halmos⁴・Marina C. Garassino⁵・Ying Cheng⁶・Erin Jensen⁷・Mark Shamoun⁷・Kumar Rajagopalan⁷・Luis Paz-Ares⁸
Department of Thoracic Oncology, Kansai Medical University Hospital, Osaka, Japan¹；Department of Internal Medicine, Henry Ford Cancer Institute/Henry Ford Health, Detroit, MI, USA²；Complejo Hospitalario Universitario Insular Materno-Infantil de Gran Canaria, Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain³；Montefiore Medical Center/Albert Einstein College of Medicine, The Bronx, NY, USA⁴；Thoracic Oncology Program, The University of Chicago Medicine ＆ Biological Sciences, Chicago, IL, USA（current affiliation）and Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy⁵；Department of Oncology, Jilin Cancer Hospital, Changchun, China⁶；Merck ＆ Co., Inc., Rahway, NJ, USA⁷；Department of Medical Oncology, Hospital Universitario 12 de Octubre, H12O-CNIO Lung Cancer Unit, Universidad Complutense ＆ Ciberonc, Madrid, Spain⁸

*Solange Peters¹・Sun Min Lim²・Ana Laura Ortega Granados³・Gustavo dix Junqueira Pinto⁴・Christian Sebastián Fuentes⁵・Giuseppe Lo Russo⁶・Michael Schenker⁷・Jin Seok Ahn⁸・Martin Reck⁹・Szijgyarto Zsolt¹⁰・Huseinovic Neda¹¹・Eleftherios Zografos¹⁰・Sean O'Donnell¹²・Filippo de Marinis¹³
Oncology Department, Centre Hospitalier Universitaire Vaudois, Lausanne University, Lausanne, Switzerland¹；Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea²；Medical Oncology Department, Hospital Universitario de Jaén, Jaén, Spain³；Department of Medical Oncology, Barretos Cancer Hospital, Barretos, São Paulo, Brazil⁴；Centro de Investigaciones Clínicas, FUNDACIÓN RESPIRAR, Buenos Aires, Argentina⁵；Medical Oncology Department 1, Thoracic Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G. Venezian 1., Milan, Italy⁶；Centrul de Oncologie, Craiova, Romania⁷；Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University, Seoul, South Korea⁸；Lungen Clinic, Airway Research Center North, Center for Lung Research, Grosshansdorf, Germany⁹；GSK, Stevenage, UK¹⁰；At the time of study conduct：GSK, Waltham, MA, USA¹¹；GSK, Collegeville, PA, USA¹²；Division of Thoracic Oncology, Istituto Europeo di Oncologia（IRCCS）di Milano, Milan, Italy¹³

*Satoshi Ikeda¹・David P. Carbone²・Tudor-Eliade Ciuleanu³・Michael Schenker⁴・Manuel Cobo-Dols⁵・Stephanie Bordenave⁶・Oscar Juan-Vidal⁷・Juliana Menezes⁸・Niels Reinmuth⁹・Eduardo Richardet¹⁰・Ying Cheng¹¹・Hideaki Mizutani¹²・Luis G. Paz-Ares¹³・Shun Lu¹⁴・Thomas John¹⁵・Xiaoqing Zhang¹⁶・Nan Hu¹⁶・David Balli¹⁶・Vipul Baxi¹⁶・Jaclyn Neely¹⁶・Martin Reck¹⁷
Kanagawa Cardiovascular and Respiratory Center, Kanagawa, Japan¹；The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA²；Institutul Oncologic Prof Dr Ion Chiricută and University of Medicine and Pharmacy Iuliu Haţieganu, Cluj-Napoca, Romania³；SF Nectarie Oncology Center, Craiova, Romania⁴；Unidad de Gestión Clínica Intercentros de Oncología Médica, Hospitales Universitarios Regional y Virgen de la Victoria, IBIMA, Málaga, Spain⁵；L'institut du Thorax, Nantes, France⁶；Hospital Universitario La Fe, Valencia, Spain⁷；Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil⁸；Asklepios Lung Clinic, Munich-Gauting, Germany⁹；IONC Instituto Oncológico de Córdoba, Cordoba, Argentina¹⁰；Jilin Cancer Hospital, Changchun, Jilin, China¹¹；Saitama Cancer Center, Saitama, Japan¹²；Hospital Universitario, 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain¹³；Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai JiaoTong University, Shanghai, China¹⁴；Austin Hospital, Heidelberg, VIC, Australia¹⁵；Bristol Myers Squibb, Princeton, NJ, USA¹⁶；Airway Research Center North, German Center for Lung Research, LungClinic, Grosshansdorf, Germany¹⁷

*Motohiro Tamiya¹・Yoshiro Nakahara^2,3・Terufumi Kato²・Reiko Isomura⁴・Toshihiro Misumi⁵・Kiyotaka Yoh⁶・Naoki Furuya⁷・Akira Ono⁸・Yuichi Takiguchi⁹・Kenichi Koyama¹⁰・Satoshi Ikeda¹¹・Kageaki Watanabe¹²・Takaaki Tokito¹³・Nobuhiko Seki¹⁴・Hisao Imai¹⁵・Takehito Shukuya¹⁶・Yuji Shibata¹⁷・Shinobu Hosokawa¹⁸・Toshiyuki Kozuki¹⁹・Hiroaki Okamoto²⁰
Department of Thoracic Oncology, Osaka International Cancer Institute¹；Department of Thoracic Oncology, Kanagawa Cancer Center²；Department of Respiratory Medicine, Kitasato University Hospital³；New Treatment Development Support Center, Kanagawa Cancer Center⁴；Department of Data Science, National Cancer Center Hospital East⁵；Department of Thoracic Oncology, National Cancer Center Hospital East⁶；Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University Hospital⁷；Division of Thoracic Oncology, Shizuoka Cancer Center⁸；Department of Medical Oncology, Chiba University Hospital⁹；Department of Internal Medicine, Niigata Cancer Center Hospital¹⁰；Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center¹¹；Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital¹²；Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University Hospital¹³；Department of Medical Oncology, Teikyo University Hospital¹⁴；Division of Respiratory Medicine, Gunma Prefectural Cancer Center¹⁵；Department of Respiratory Medicine, Juntendo University Hospital¹⁶；Department of Respiratory Medicine, National Hospital Organization Yokohama Medical Center¹⁷；Department of Respiratory Medicine, Japanese Red Cross Okayama Hospital¹⁸；Department of Thoracic Oncology and Medicine, National Hospital Organization Shikoku Cancer Center¹⁹；Department of Respiratory Medicine, Yokohama Municipal Citizen's Hospital²⁰

*Koichi Azuma¹・Hiromi Nagashima²・Yu Utsumi²・Tatsuro Fukuhara³・Aya Suzuki³・Masahiro Seike⁴・Akihiko Miyanaga⁴・Akira Kisohara⁵・Yosuke Kawashima⁶・Hajime Asahina⁷・Hisashi Tanaka⁸・Ryota Kanemaru⁹・Eisaku Miyauchi¹⁰・Naoki Furuya¹¹・Haruna Sato¹²・Kazuhisa Nakashima¹³・Kazuko Sakai¹⁴・Kazuto Nishio¹⁴・Fumiaki Takahashi²・Kunihiko Kobayashi¹⁵・Makoto Maemondo^2,12
Kurume University¹；Iwate Medical University²；Miyagi Cancer Center³；Nippon Medical School⁴；Kasukabe Medical Center⁵；Sendai Kousei Hospital⁶；Hokkaido University⁷；Hirosaki University⁸；Juntendo University⁹；Tohoku University¹⁰；St. Marianna University¹¹；Jichi Medical University¹²；Shimane University¹³；Kindai University¹⁴；Saitama Medical University¹⁵

*吉岡　弘鎮^1,3・三浦　　理^2,3・三角　俊裕³・倉田　宝保^1,3・時任　高章³・福原　達朗³・佐藤　悠城³・白石　祥理³・楠原政一郎³・寺岡　俊輔³・加藤　晃史³・堀之内秀仁³・滝口　裕一³・後藤　康洋³・田中謙太郎³・金津　正樹³・池田　　慧³・市原　英基³・田中　洋史^2,3・岡本　浩明³
関西医科大学附属病院¹；新潟県立がんセンター新潟病院²；胸部腫瘍臨床研究機構（TORG）³

*中島　和寿^1,2・宮永　晃彦²・西岡　安彦²・窪田　哲也²・石川　暢久²・渡邉　香奈²・三浦　啓太²・大湾　勤子²・桂田　直子²・横山　彰仁²・服部　　登²・小林　国彦²・礒部　　威^1,2・津端由佳里^1,2
島根大学医学部内科学講座呼吸器・臨床腫瘍学¹；ENSURE-GA研究グループ²

*Fumihiro Tanaka¹・Jonathan Spicer²・Patrick Forde³・Mariano Provencio⁴・Shun Lu⁵・Changli Wang⁶・Tetsuya Mitsudomi⁷・Stephen Broderick³・Scott J. Swanson⁸・Mark M. Awad⁸・Enriqueta Felip⁹・Julie Brahmer³・Keith Kerr¹⁰・Gene B. Saylors¹¹・Ke-Neng Chen¹²・Junliang Cai¹³・Javed Mahmood¹³・Nan Hu¹³・Phuong Tran¹³・Nicolas Girard¹⁴
University of Occupational and Environmental Health, Kitakyushu, Japan¹；McGill University Health Centre, Montréal, QC, Canada²；Johns Hopkins Medicine, The Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA³；Hospital Universitario Puerta de Hierro, Madrid, Spain⁴；Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China⁵；Tianjin Lung Cancer Center, Tianjin Medical University Cancer Institute ＆ Hospital, Tianjin, China⁶；Kindai University Faculty of Medicine, Ohno-Higashi, Osaka-Sayama, Japan⁷；Dana-Farber Cancer Institute, Boston, MA, USA⁸；Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, Spain⁹；Aberdeen Royal Infirmary, Aberdeen, UK¹⁰；Charleston Oncology, Charleston, SC, USA¹¹；Peking University Cancer Hospital and Institute, and Beijing Cancer Hospital, Beijing, China¹²；Bristol Myers Squibb, Princeton, NJ, USA¹³；Institut du Thorax Curie-Montsouris, Institut Curie, Paris, France¹⁴

*Toshiaki Takahashi¹・Benjamin Besse²・Gilberto de Castro³・Enriqueta Felip⁴・Katerina Politi⁵・Jie Wang⁶・Emma Dean⁷・Melissa Deans⁸・Helen Broadhurst⁷・Piruntha Thiyagarajah⁷・Patrick Forde⁹
Shizuoka Cancer Center, Japan¹；Institut Gustave Roussy, France²；Instituto do Câncer do Estado de São Paulo, Brazil³；Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Spain⁴；Yale Cancer Center, USA⁵；Cancer Hospital, Chinese Academy of Medical Sciences, China⁶；AstraZeneca, UK⁷；AstraZeneca, Canada⁸；Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, USA.⁹

*Koichi Goto¹・Herbert H. Loong²・Benjamin J. Solomon³・Keunchil Park⁴・Maurice Pérol⁵・Edurne Arriola⁶・Silvia Novello⁷・Ying Cheng⁸・Andrea Ardizzoni⁹・Milena P. Mak¹⁰・Fernando C. Santini¹¹・Yasir Y. Elamin¹²・Alexander Drilon¹³・Jürgen Wolf¹⁴・Baohui Han¹⁵・Hongmei Han¹⁶・Minji K. Uh¹⁷・Tarun Puri¹⁷・Viktoriya Ilaria¹⁷・Caicun Zhou¹⁸
National Cancer Center Hospital East¹；Chinese University of Hong Kong, Hong Kong²；Peter MacCallum Cancer Institute³；Samsung Medical Center⁴；Centre Léon Bérard⁵；Hospital del Mar⁶；AOU San Luigi-Orbassano, University of Turin⁷；Jilin Cancer Hospital⁸；IRCCS Azienda Ospedaliero-Universitaria di Bologna⁹；Instituto D'Or de Pesquisa e Ensino¹⁰；Hospital Sírio Libanês¹¹；The University of Texas MD Anderson Cancer Center¹²；Memorial Sloan Kettering Cancer Center¹³；University Hospital of Cologne¹⁴；Shanghai Chest Hospital¹⁵；Loxo@Lilly¹⁶；Eli Lilly and Company¹⁷；Shanghai Pulmonary Hospital¹⁸