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Vol.37 No.6 contents | Japanese/English |
- Case Report -
A Case of Adenocarcinoma of the Lung Associated with Giant Emphysematous Bulla Treated with Simultaneous Cisplatin, 5-fluorouracil, and Hyperfractionated Thoracic Irradiation
Takuji Kitajima, Hiroshi Ueoka, Katsuyuki Kiura, Masahiro Tabata, Mine Harada and Nobuyoshi Simizu*The Second Department of Internal Medicine, *The Second Department of Surgery, Okayama University School of Medicine
A 48-year-old man was referred to us, of a mass shadow in the infected emphysematous bulla by chest CT scannings. Neither bronchofiberscopic examination nor CT-guided transcutaneous biopsy could yielded a definitive diagnosis. By surgical resection of the extrapleural tumor directly invading the chest wall, poorly differentiated adenocarcinoma was diagnosed. Three cycles of chemotherapy consisting of cisplatin (20 mg/m2×5 days) and 5-fluorouracil (500 mg/m2×5 days), and simultaneous hyperfractionated thoracic irradiation (70 Gy in a total dose with 1.25 Gy×2/day) were immediately started and the mass shadow markedly regressed. Lung cancer with a coexisting bulla is frequently advanced and considered to have poor prognosis. Chemoradiotherapy may be useful for the treatment of unresectable advanced cases.
key words: Lung cancer, Giant emphysematous bulla, Chemo-radiotherapy
Received: March 17, 1997
Accepted: July 24, 1997
JJLC 37 (6): 913-917, 1997
