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Vol.38 No.1 contents | Japanese/English |
- Case Report -
A Case of Bronchioloalveolar Carcinoma with BOOP Pattern Lesion Diagnosed by Open Lung Biopsy
Takahiro Morisako, Hideo Kobayashi, Naokazu Nagata, Teruhiro Aoki*, Shinsuke Aida** and Seiichi Tamai**The Third Department of Internal Medicine National Defense Medical College, Tokorozawa, Saitama, Japan, *The Second Department of surgery, **The Department of Clinical pathology
A 75-year-old man was admitted to our hospital because of multiple infiltrative shadows on a chest roentgenogram. Infiltrative shadows had progressed subacutely in comparison to the findings of 3 months previously. Chest CT scans demonstrated air space consolidation containing bubble-like areas. Sputum and bronchial washing cytology were negative. Bronchoalveolar lavage revealed an elevation of lymphocyte fraction. Open lung biopsy (OLB) was performed to make a distinction between idiopathic BOOP and other diseases. The specimen obtained by OLB histlogically revealed BOOP pattern in the bronchioles and alveolar ducts,showing granulation tissue with proliferation of fibroblasts, and bronchioloalveolar carcinoma with mucin-producing cells (BAC), in which small cystic spaces were observed with mucus in alveoli. We concluded that TBLB was important in the case of air space consolidation with bubble-like areas of low attenuation on the chest CT because mucin in the alveoli with or without malignant cells highly suggested BAC.
key words: Bronchioloalveolar cell carcinoma, Goblet cell type, BOOP, Open lung biopsy
Received: January 6, 1997
Accepted: December 11, 1997
JJLC 38 (1): 69-73, 1998
