タイトル
Vol.38 No.3 contents Japanese/English

- Case Report -

Synchronous Multiple Primary Lung Cancer Comprising Small-Cell Carcinoma and Adenocarcinoma: Report of a Case

Koji Onishi, Akio Hiraki, Hiroshi Ueoka, Akio Ando*, Nobuyoshi Shimizu* and Mine Harada
Department of Internal Medicine II, *Surgery II, Okayama University Medical School

An abnormal shadow was found out on the chest radiograph of 57-year-old Japanese man during a regular check-up. A CT scan of the chest at a local clinic demonstrated a nodule in the right upper lobe. He was admitted to our hospital. Transbronchial lung biopsy yielded a diagnosis of moderately differentiated adenocarcinoma of the lung, A CT scan of the chest revealed swelling of the subcarinal lymph nodes. He underwent mediastinoscopy for subcarinal lymph node biopsy, and a diagnosis of a small cell carcinoma, intermediate cell type, was made. He was treated with concurrent radiotherapy and chemotherapy consisting of cisplatin and etoposide. He achieved a partial response for small cell lung carcinoma and a minor response for the adenocarcinoma. He was further treated with thoracoscopic resection of the adenocarcinoma and mediastinal lymph node dissection. No residual tumor cells were detected in the mediastinal lymph nodes. Only a few cases of synchronous primary lung cancer comprising small cell and non-small cell have been reported.
key words: Synchronous multiple primary lung cancer, Mediastinoscopy, Small cell lung cancer

Received: November 26, 1997
Accepted: April 27, 1998

JJLC 38 (3): 261-265, 1998

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