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Vol.40 No.2 contents | Japanese/English |
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- Case Report -
A Case of ACTH-producing Thymic Carcinoid Tumor with Cushing's Syndrome
Motoki Sakuraba, Masahiro Mae, Takamasa Onuki, Kunihiro Oyama, Hirosi Komine, and Sumio NittaDepartment of Surgery I, Tokyo Women's Medical University
Case: A rare case of ACTH-producing thymic carcinoid is reported. A 42-year-old man was admitted because of hyperglycemia and hypertension. Endocrinological examination revealed high plasma ACTH and serum cortisol levels. Cushing's syndrome, i. e.osteoporosis, pigmentation, hypertension, hyperglycemia, and moonface, was recognized. No tumor was seen in the pituitary gland and adrenal gland. We suspected an ectopic ACTH-producing tumor. An anterior mediastinal tumor was detected on chest CT. The tumor was totally resected through median sternotomy. Histopathologically the tumor was stained with synaptophysin, NSE, chromogranin-A and ACTH. After the operation, hyperglycemia was recovered and plasma ACTH levels decreased.
key words: Thymic carcinoid, ACTH-producing tumor, Cushing's syndrome
Received: November 10, 1999
Accepted: January 21, 2000
JJLC 40 (2): 117-120, 2000
