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Vol.40 No.2 contents

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- Case Report -

Squamous Cell Carcinoma of the Trachea in a Non-smoking Woman after Radiation Therapy for Breast Cancer

Naoki Ishiwa^1,3, Kouzou Yamada¹, Haruhiko Nakayama¹, Kazumasa Noda¹, Youichi Kameda³ and Takamitsu Maehara^3
1Department of Thoracic Diseases, ²Department of Pathology, Kanagawa Cancer Center, ³First Department of Surgery, Yokohama City University

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Few cases of squamous cell carcinoma of the trachea have been reported in non-smoking women. We report one case which was probably due to radiation therapy. Case: A 50-year-old non-smoking woman was referred to our hospital because wheezing and dyspnea had been aggravated for 3 months. She had received radiation therapy (⁶⁰Cobalt) after standard radical mastectomy for right breast cancer 13 years previously. Bronchoscopic findings and chest CT scan showed tracheal stenosis due to the tumor. Sleeve resection of the trachea was performed, and the tumor was histologically diagnosed as poorly differentiated squamous cell carcinoma. Conclusion: We may consider this case to be radiation-induced cancer compatible with the most strict criteria of radiation induced malignancy.
key words: Tracheal tumor, Squamous cell carcinoma, Radiation induced malignancy, Radiotherapy, Breast cancer

Received: October 13, 1999
Accepted: February 4, 2000

JJLC 40 (2): 133-137, 2000