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Vol.40 No.6 contents | Japanese/English |
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- Original Article -
Changes in the Proportions of Histologic Types and Clinical Features of Primary Lung Cancer from the 1980s to the 1990s
Yoshihiro Okamoto, Koichi Yamazaki, Toshiyuki Harada, Tetsuya Kojima, Fumihiro Honmura, Akira Kamimura, Hiromitsu Hiroumi, Shigeaki Ogura, Hirotoshi Akita and Yoshikazu KawakamiFirst Department of Medicine, Hokkaido University School of Medicine, Sapporo 060-8638, Japan
Objective: We analyzed changes in the proportions of histologic types and clinical features of primary lung cancer from the 1980s to the 1990s. Study Design: Of 755 cases who were admitted to our hospital between 1983 and 1998,762 primary lung cancer cases were investigated retrospectively. They were divided into two groups, according to year of admission: 1983∼1990 (1980s) and 1991∼1998 (1990s). Results: There were no significant differences between the 1980s and the 1990s in the total number of primary lung cancer cases, the ratio of sex, smokers, the reason for detection, the clinical stages or the treatment provided, however, the patients in the 1990s were significantly younger than those in the 1980s (p<0.05). The ratio of adenocarcinomas to total cases increased from 46.2% (1980s) to 56.9% (1990s) (p<0.005), especially in males (p<0.005), smokers (p<0.005), and middle-aged groups (those in their 50s and 60s). In male smokers, the proportion of adenocarcinomas increased from 27% (1980s) to 46% (1990s) (p<0.001), whereas the proportion of squamous cell carcinomas decreased from 42% (1980s) to 30% (1990s) (p<0.05). Conclusion: Although this study was limited by the small population of cases admitted only in our department, it may be useful in investigating the trends of the histologic types of primary lung cancer and in reconsidering the medical care of primary lung cancer patients.
key words: Primary lung cancer, Histologic type, Adenocarcinoma, Squamous cell carcinoma, Time trend
Received: April 10, 2000
Accepted: July 25, 2000
JJLC 40 (6): 609-614, 2000
