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Vol.41 No.1 contents | Japanese/English |
 | Full Text of PDF (384K) Article in Japanese |
- Original Article -
Results of Pulmonary Resection of Metastatic Colorectal Cancer
Mitsuo Kawamura, Yasuhiro Takahashi, Kimito Orino and Yoshirou SazawaNakadohri General Hospital, Akita, Japan
Objective: To clarify the long-term outcome and indication of pulmonary resection for metastatic colorectal cancer. Design: A retrospective study. Methods and Results: We analyzed the outcome of 21 patients who underwent surgery (24 operations) for pulmonary metastases of colorectal cancer. Median disease-free interval between colon and lung resection was 25 months (range, 0 to 85 months). Seventeen patients (80%) had a solitary metastasis. Partial resection was performed in 9 patients, segmentectomy in 1 and lobectomy in 11. Median follow-up was 48 months (range, 8 to 147 months). Overall 5-and 10-year survival rate was 46.9% and 23.4%, respectively. Four patients who survived 5 years or more without any evidence of recurrence were limited to those with a solitary and completely resected pulmonary metastasis. Two of them were alive more than 10 years. Most patients with multiple lung metastases or extrapulmonary metastases died of multiple systemic metastases within 2 years. Conclusions: We concluded that multiple lung metastases or extrapulmonary metastases were poor prognostic factors in patients with colorectal cancer. Since we had some cases with slow growing tumors, long-term follow-up (more than 5 years) including final outcome is necessary for accurate evaluation.
key words: Colorectal cancer, Metastatic lung tumor, Surgical treatment
Received: October 24, 2000
Accepted: December 26, 2000
JJLC 41 (1): 39-43, 2001
