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Vol.41 No.1 contents | Japanese/English |
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- Case Report -
A Case of Adenocarcinoma of the Lung Which Highly Responded to Neoadjuvant Chemoradiotherapy
Yoko Ishibashi1, Yoshio Tokuchi1, Masafumi Kamachi1, Masao Harada1, Hiroshi Isobe1 and Kenji Okayasu21Department of Pulmonary Disease, National Sapporo Hospital, 2Department of Respiratory Surgery, Keiyukai Sapporo Hospital
Background: Since the prognosis of patients with stage IIIA N2 non-small cell lung cancer is poor, investigation of combined modality therapy is necessary. Case: The patient was a 53-year-old man. He was admitted because of an abnormal shadow on his chest X-ray film. He received a diagnosis of adenocarcinoma of the lung, T1N2M0, stage IIIA. Because of the bulky lymph node, neoadjuvant chemotherapy was performed. After chemotherapy (Cisplatin 25 mg/m2, day 1, 8, 15+Docetaxel 20 mg/m2,day 1, 8, 15) with concurrent radiotherapy (40 Gy/16fr), #2 lymph node was reduced and primary lesion was detected only as a scar. After chemoradiotherapy right upper lobectomy with regional lymph node dissection (ND2a) was performed. Microscopic findings of the resected specimen showed no tumor tissue. Conclusion: We describe our experience with an advanced non-small cell lung cancer which achieved complete response after chemoradiotherapy. This result indicates that neoadjuvant chemoradiotherapy before surgical resection might be useful.
key words: Lung cancer, Non-small cell lung cancer (NSCLC), Neoadjuvant therapy, Chemoradiotherapy, Combined modality therapy
Received: April 7, 2000
Accepted: November 10, 2000
JJLC 41 (1): 65-68, 2001
