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Vol.41 No.4 contents | Japanese/English |
 | Full Text of PDF (340K) Article in Japanese |
- Case Report -
A Case of Endobronchial Metastasis From Pancreatic Islet Cell Carcinoma
Yutaka Nishigaki, Yoshinobu Ohsaki, Kyoko Nakanishi, Yasushi Yamamoto, Hiroshi Ide and Kenjiro KikuchiFirst Department of Internal Medicine, Asahikawa Medical Collage
Background: Islet cell tumor is a rare tumor of pancreatic origin. Spread of islet cell tumor is usually found in regional lymph nodes and the liver. Metastasis to the lung is uncommon. Case: A 48-year-old man with wheezing and dyspnea on effort was admitted. Chest radiography and computed tomography revealed a large mass shadow with a low density area in the left lower lung field. Bronchoscopy showed obstruction of left main bronchus by a polypoid tumor accompanied by necrosis. Histological findings of the transbronchial biopsy specimen showed the tumor to consist of cords and solid sheets of small cells with round regular nuclei. Tumor cells positively stained for synaptophysin immunostaining. These histological findings resembled those of the pancreatic primary lesion. Bone scintigram showed multiple abnormal uptake areas. We concluded that the pulmonary lesion was an endobronchial metastatic islet cell tumor. The patient was treated with Nd YAG laser and the polypoid tumor in the left main bronchus decreased in size. Conclusion: We encountered a rare case with lung and bone metastases from pancreatic islet cell tumor. In this case, the endobronchial metastatic lesion decreased in size following laser therapy.
key words: Islet cell carcinoma, Lung metastasis, Bone metastasis, Endobronchial metastasis
Received: January 22, 2001
Accepted: June 7, 2001
JJLC 41 (4): 333-336, 2001
