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Vol.43 No.4 contents | Japanese/English |
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- Case Report -
A Case of Advanced Thymic Carcinoma Completely Resected After Chemoradiotherapy
Hirokazu Tanaka1, Toshiaki Wakayama2, Masaharu Nakade1, Hiroyoshi Watanabe1, Keijiro Kono1, Masayuki Shintaku3Department of 1Chest Surgery, 2Respiratory Medicine, 3Pathology, Osaka Red Cross Hospital, Japan
Background. Standard treatment for advanced thymic carcinoma has not yet been established, and the prognosis is very poor. Case. A 49-year-old man suffered from undifferentiated thymic carcinoma with superficial cervical lymph node metastasis, corresponding to stage IVB of Masaoka's classification. He was treated with two cycles of chemotherapy consisting of paclitaxel and carboplatin, and concurrent radiotherapy of 40 Gy. The reduction rate of the tumor size was 77.4%, enabling it to be completely resected. The pathological examination revealed neither residual tumor cells in the resected specimen nor lymph node metastasis. Two cycles of postoperative chemotherapy with the same regimen and concurrent radiotherapy of 20 Gy were added. Conclusion. Preoperative chemotherapy with paclitaxel and carboplatin, and concurrent radiotherapy might be effective in advanced thymic carcinoma.
key words: Undifferentiated thymic carcinoma, Chemotherapy, Paclitaxel, Carboplatin, Radiation
Received: March 3, 2003
Accepted: May 20, 2003
JJLC 43 (4): 335-340, 2003
