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Vol.43 No.7 contents | Japanese/English |
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A Case of Locally Advanced Non-small-cell Lung Cancer (Pathological CR) Completely Resected After Chemotherapy (Cisplatin+Docetaxel Regimen)
Sakae Okumura11Division of Chest Surgery Cancer Institute Hospital
Background. Standard treatment for locally advanced non-small-cell lung cancer has not yet established. Case. The patient was 58-year-old man with locally advanced squamous cell carcinoma (cT4N2M0, stage IIIB). The tumor, which was directly invading subcarinal lymph nodes and the esophagus, was located in the subcarinal space. He was treated with three cycles of chemotherapy with cisplatin and docetaxel. The reduction rate of the tumor size was 59%. No findings of the invasion to the esophagus were recognized after chemotherapy, enabling it to be completely resected. The operation of bilobectomy of right middle and lower lobe with combined resection of the subcarinal lymph nodes and the muscle layer of esophagus was performed. The pathological examination revealed neither residual tumor cells in the resected specimen nor lymph node metastasis, only fibrosis. Conclusion. Preoperative chemotherapy with cisplatin and docetaxel might be effective in locally advanced non-small cell lung cancer patients.
key words: Locally advanced non-small-cell lung cancer, Chemotherapy, Cisplatin, Docetaxel, Complete Response
JJLC 43 (7): 968-973, 2003
