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Vol.45 No.3 contents | Japanese/English |
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- Case Report -
Two Cases of Pulmonary Lymphomatoid Granulomatosis With Different Outcomes
Tomoyuki Nakagiri1, Akinori Akashi1, Norihisa Shigemura1, Yoshinobu Matsuda2, Seiichi Nobuyama2Department of 1General Thoracic Surgery, 2Pulmonary Medicine, Takarazuka Municipal Hospital, Japan
Background. Lymphomatoid granulomatosis is a very rare disease, with only 11 cases having been reported in Japan. We report different outcomes in two cases of pulmonary lymphomatoid granulomatosis. Cases. Case 1 involved a 68-year-old woman who had an abnormal pulmonary hilar shadow on chest radiography. Bronchoscopy did not assist diagnosis, so partial resection of the lung was performed under video-assisted thoracic surgery. Frozen section examination suggested lung cancer. Right middle lobectomy with dissection of the mediastinal lymph nodes was performed. Histopathology revealed grade III lymphomatoid granulomatosis. Adjuvant chemotherapy proved ineffective and the patient died 10 months postoperatively. Case 2 involved a 71-year-old woman who also had an abnormal shadow on chest radiography. Bronchoscopy again proved unhelpful, so partial resection of the lung was performed under video-assisted thoracic surgery. Frozen section examination yielded a diagnosis of lymphomatoid granulomatosis, and histopathology confirmed grade I lymphomatoid granulomatosis. The patient remains alive without any sign of recurrence at 1 year postoperatively. Conclusion. We report these 2 cases and review the reports of lymphomatoid granulomatosis in Japan.
key words: Lymphomatoid granulomatosis, Grade
Received: November 15, 2004
Accepted: March 30, 2005
JJLC 45 (3): 249-254, 2005
