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Vol.45 No.4 contents | Japanese/English |
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- Case Report -
A Case of Rapidly Progressing Pulmonary Spindle Cell Carcinoma
Kazutoshi Hamanaka1, Masayuki Toishi1, Hideki Nishimura11Department of Chest Surgery, Nagano Municipal Hospital, Japan
Background. Pulmonary spindle cell carcinoma which consists of only spindle cells, has a poor prognosis. We report a patient who died after rapid progress of the disease, following lung and chest wall resection. Case. A 68-year-old man was admitted because of lung cancer which invaded his chest wall. Chest computed tomography revealed a 7 cm tumor, located in S6 of the left lung, and contained a cavity. Distant metastases could not be detected. Left lower lobectomy and chest wall resection were performed about 6 weeks after symptom appeared. Histological findings revealed only spindle cells, and immunohistochemical stain showed it was cytokeratin positive. We diagnosed pulmonary spindle cell carcinoma. The patient was admitted to another hospital about 5 weeks after the operation because of bowel obstruction. Emergency operation was performed. Resected intestinal tumors were diagnosed as metastases of spindle cell carcinoma. Subsequently, local recurrence, lung and bone metastases were detected. The patient died 6 months after the lung operation. Conclusion. Pulmonary spindle cell carcinoma is commonly regarded as having a poor prognosis. We should perform aggressive adjuvant therapy after surgery for this disease.
key words: Pulmonary spindle cell carcinoma, Immunohistochemical stain, Cytokeratin
Received: December, 2004
Accepted: April 21, 2005
JJLC 45 (4): 363-366, 2005
