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Vol.45 No.6 contents Japanese/English

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Article in Japanese

- Case Report -

A Case of MALT Lymphoma of Lung

Kazuhiro Washio1, Hideyuki Nishi1, Sae Wada2, Kenichi Genba2
Department of 1Surgery, 2Respiratory, Okayama Rosai Hospital, Japan

We report a case of MALT lymphoma of the lung. Case. A 67-year-old woman was referred to our hospital because of atelectasis in the S3 of the right lung, which had not been improved during the previous 1 year. She had a past history of abnormal chest shadow of the right upper lung field 3 years previously. Chest computed tomography (CT) scanning showed an infiltrative shadow, spreading from the central to pleural region of the S3. The margin was sharp and there was an air bronchogram. The serum level of various tumor markers was within the normal range. Transbronchial biopsy specimen revealed mucosa-associated lymphoid tissue (MALT) lymphoma. Additional examinations including Ga scintigraphy showed no abnormal lesion except for the S3 lesion. She underwent right upper sleeve lobectomy with lymph-node dissection. Although the post-operative histopathologic examination suggested invasion at the bronchial stump, she did not receive adjuvant chemotherapy or additional radiation therapy. Conclusion. Surgery is considered to be a useful treatment for pulmonary MALT lymphoma of the localized type, based on previous several observations, however it has not been clarified whether complete resection is the most effective in terms of prognosis. Considering the difficulty in frozen section diagnosis, uncertain effect of chemotherapy or radiation therapy and invasion of extended damage due to radical resection, further examination is necessary to determine the best treatment.
key words: Lung, Mucosa-associated lymphoid tissue lymphoma (MALT), Treatment

Received: January 31, 2005
Accepted: July 26, 2005

JJLC 45 (6): 729-733, 2005

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