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Vol.46 No.2 contents Japanese/English

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Article in Japanese

- Original Article -

Three Cases of Non-Small Cell Lung Cancer Associated with Skeletal Muscle Metastases

Tomoyuki Araya1, Kazuo Kasahara1, Masaki Fujimura1, Yuichi Tanbo1, Shunichi Tamori1, Takashi Sone1, Shinji Nakao1
1Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan

Background. Skeletal muscle metastases from lung cancer are considered to be extremely rare. We encountered 3 cases of lung cancer associated with skeletal muscle metastases on initial medical examination or during disease progression. Cases. Case 1: A 46-year-old man was trismic due to metastasis of lung adenocarcinoma to the lateral pterygoid muscle. He was resistant to radiotherapy and chemotherapy, and died 9 months after the occurrence of symptoms. Case 2: A 57-year-old man had a large cell lung carcinoma or poorly differentiated lung adenocarcinoma. He had metastasis to the right femoral muscle in addition to multiple metastases to many other organs. His disease was also resistant to any treatment, and died 7 months after he became symptomatic. Case 3: A 64-year-old man with adenocarcinoma had a single metastasis to the biceps muscle. He died 3 months after the diagnosis of muscle metastasis due to resistance to therapy. Conclusion. Upon diagnosis of tumorous lesions of skeletal muscles, whole body examination and subsequent percutaneous biopsy of muscle involvement are required to determine the possibility of skeletal muscle metastasis of lung cancer.
key words: Non-Small Cell Lung Cancer, Skeletal Muscle Metastases, Chemotherapy, Prognosis

Received: November 28, 2005
Accepted: January 20, 2006

JJLC 46 (2): 117-125, 2006

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