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Vol.46 No.2 contents | Japanese/English |
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- Case Report -
A Long-term Surviving Case of Recurrent Adrenal Metastasis of Lung Cancer Treated by Uracil-Tegafur
Norifumi Abe1, Noriko Yamada1, Teruo Ishihara1, Ritsu Kohiyama21Department of Respiratory Tract Surgery, Kanto Medical Center NTT, Japan, 2Department of Respiratory Tract Surgery, Japanese Red Cross Society Fukaya Hospital, Japan
Background. Metastatic adrenal tumors are frequently found at autopsy in patients with lung cancer. In recent years, metastases have been detected earlier because of the advances in diagnostic radiology. There have been an increase in reports that adrenalectomy improved the prognosis. However, there is no effective treatment for local recurrence after adrenalectomy. We encountered a long-term survivor who responded remarkably to treatment with uracil-tegafur (UFT). Case. A 71-year-old man underwent left lower lobectomy for lung cancer (adenocarcinoma, pT2N0M0 stage IB). Five months later, CT scan showed a right adrenal tumor. Adrenalectomy was performed, and a histopathological diagnosis of metastatic adrenal tumor was given. Local recurrence was noted 3 months later, with the tumor gradually invading upon the liver. UFT (300 mg/day) was administered, resulting in a reduction in the size of the tumor. Eight months later, the tumor had disappeared on CT. Three and a half years after the adrenalectomy, the patient is alive without further recurrence. Conclusion. These findings indicate the efficacy of UFT in a case of adrenal metastasis of non-small cell lung cancer.
key words: Adrenal metastasis, Lung cancer, Chemotherapy, UFT
Received: January 5, 2006
Accepted: March 13, 2006
JJLC 46 (2): 161-165, 2006
