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Vol.47 No.2 contents Japanese/English

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Article in Japanese

- Case Report -

A Case of Mandibular Ameloblastoma with Multiple Lung Metastases

Tomoe Sawazumi1,2, Haruhiko Aisaka1,2, Junya Kitada2, Hiroki Takahashi2, Shosaku Abe3
1Department of Respiratory Internal Medicine, Kitami Douritsu Hospital, Japan, 2Third Department of Medicine, Sapporo Medical University, Japan, 3Sapporo Minami-sanjo Hospital, Japan

Background. Ameloblastoma is one of the odontogenic tumors, and accounts for about 60% of all odontogenic tumors. Malignant ameloblastoma with distant metastasis is rare. We present here a patient who had a mandibular ameloblastoma with multiple pulmonary metastases. Cases. A 65-year-old woman was referred to our hospital in December 1987 because of a chest abnormal shadow. The chest radiograph showed multiple nodules in both lungs. A thorough examination failed to reach a diagnosis. She was followed up until 2001, because she had no symptom until that time. She was referred to our hospital again because of hemoptysis and was admitted in October 2002. The multiple lung nodules had increased on the chest radiography. She underwent an operation for lung biopsy by video-assisted thoracoscopy (VATS) to establish a definitive diagnosis in November 2002. Pathologically, they were diagnosed as metastatic ameloblastoma, for which she had been operated in August 1965. Conclusion. Metastatic ameloblastoma arose after more than 20 years since her operation for primary mandibular ameloblastoma. This case is also rare because she is alive at over 15 years from when the pulmonary metastasis was pointed out.
key words: Odontogenic tumor, Ameloblastoma, Multiple pulmonary metastases

Received: February 9, 2006
Accepted: February 16, 2007

JJLC 47 (2): 143-147, 2007

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