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Vol.47 No.3 contents Japanese/English

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Article in Japanese

- Original Article -

Evaluation of Mediastinal Node Metastasis in Lung Cancer by FDG-PET

Masashi Kobayashi1, Kenichi Okubo2, Hiromasa Morikawa2, Eichi Hayatsu2
1Department of Surgery, Hyogo Prefectural Amagasaki Hospital, Japan, 2Department of Thoracic Surgery, National Hospital Organization Nagara Medical Center, Japan

Objective. We evaluated the diagnostic capability of PET scan concerning mediastinal lymph node metastasis in lung cancer. Patients and Methods. From January 2003 to May 2005, 100 patients with lung cancer underwent PET scan and subsequent histopathological examination for lymph node metastasis. The accuracy of the diagnostic rate of PET scan for mediastinal node metastasis diagnosis and hilar node metastasis was examined in these patients. Results. PET scan results for mediastinal node metastasis diagnosis yielded nine false positive, and 13 false negative. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of PET scan were 35%, 88.8%, 43.8%, 84.5%, and 78%, respectively. Eight patients shown to be N-disease by PET scan were pathologically diagnosed as N2 diseases in 4, N1 in 1, and N0 in 3, which indicated a 12.5% accuracy rate for PET scan. Conclusion. The diagnostic accuracy of PET scan for mediastinal node metastasis was poor.
key words: Lung cancer, FDG-PET, Mediastinal lymph node

Received: June 6, 2006
Accepted: February 20, 2007

JJLC 47 (3): 233-238, 2007

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