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Vol.47 No.7 contents Japanese/English

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Article in Japanese

- Case Report -

A Case of MALT Lymphoma with Pleural Effusion

Hirokazu Tokuyasu1, Etsuko Watanabe1, Hirokazu Touge1, Yuji Kawasaki1, Ryo Maeda2, Noritaka Isowa2
Divisions of 1Respiratory Medicine, 2Thoracic Surgery, Matsue Red Cross Hospital, Japan

Background. We report a rare case of mucosa-associated lymphoid tissue (MALT) lymphoma accompanied by pleural effusion. Case. A 78-year-old man, on human T-cell lymphotropic virus type-1 (HTLV-1) carrier, was found to have a nodular lesion in the right lower lung field on a screening chest radiography in 1998. Transbronchial biopsy did not yield a diagnosis. The lesion increased during follow-up, and he was readmitted due to dyspnea on exertion in November 2001. Chest radiography and CT scan showed an ill-defined mass in the right lower lobe with pleural effusion. Pleural puncture revealed bloody, exudative, lymphocytic pleural effusion. The diagnosis obtained after middle and lower bilobectomy was MALT lymphoma by immunohistochemical and gene analysis of tissue specimens. He received no adjuvant chemotherapy and is still alive without recurrence 65 months after the operation. Conclusion. Complete resection may improve the outcome of pulmonary MALT lymphoma even if it is accompanied by pleural effusion.
key words: MALT (mucosa-associated lymphoid tissue) lymphoma, Pleural effusion, HTLV-1 (human T-cell lymphotropic virus type-1) carrier

Received: August 1, 2007
Accepted: October 11, 2007

JJLC 47 (7): 891-896, 2007

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