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Vol.47 No.7 contents | Japanese/English |
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- The 21st Lung Cancer Workshop -
Present Status of Clinical Cytopathology of Respiratory Organs
Tomio Nakayama1, Akemi Takenaka1, Junji Uchida1, Fumio Imamura1, Masahiko Higashiyama1, Ken Kodama11Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan
Objective. Small sized peripheral lung lesions are often resected without obtaining cytopathological diagnosis based on the result of advanced imaging technique. We have improved the preoperative diagnostic accuracy and provided information on prognosis by using the technique of a rapid cytological diagnosis. Method and Result. We used modified rapid Shorr stain as a rapid cytology test, by which we could immediately report cytological diagnosis in about one minute. In bronchoscopy, when rapid cytology test yielded no diagnosis, additional bronchoscopic examinations were performed. The integration of rapid cytology test into bronchoscopic examination improved diagnostic sensitivity of lung cancer of 2 cm or less from 64% to 92%. Moreover, the tumor stamp cytology of resected adenocarcinoma of 2 cm or less was classified into 5 types, and relationship with the prognosis was clarified. The prospective study to verify whether this classification adds to the decision for limited operation is ongoing. Conclusion. The cytopathlogy of respiratory organ can promptly offer various information as long as an appropriate specimen is obtained.
key words: Lung cancer, Cytopathology, Rapid staining
JJLC 47 (7): 941-943, 2007
