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Vol.48 No.4 contents Japanese/English

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Article in Japanese

- The 33rd Diagnostic Imaging Seminar -

Usefulness of Endobronchial Ultrasonography for Diagnosis of Lung Cancer

Noriaki Kurimoto1, Hiroaki Osada2
1Department of Surgery, Division of Chest Surgery, St. Marianna University, School of Medicine, Japan, 2Department of Surgery, Shonan Chuoh Hospital, Japan

The applications of EBUS are 1) determination of the depth of tracheobronchial tumors, 2) EBUS-guided trans-bronchial needle aspiration (TBNA), 3) differential diagnosis of peripheral lung lesions, 4) detection of the precise location of peripheral pulmonary lesions. We evaluated 150 lesions by EBUS using a thick guide sheath (GS) (2.5 mm in diameter) covering a miniature probe, in a prospective open study. In the procedure of EBUS-GS, the probe covered by a guide sheath is introduced into the lesion via the working channel of a bronchoscope. The probe is withdrawn, while the guide sheath is left in place. A brush or biopsy forceps is then introduced through the guide sheath into the lesion. EBUS visualized the image in 93% of the peripheral pulmonary lesions. Diagnosis was made in 116 (77%) of the 150 EBUS-GS procedures. Cases in which the probe was located within the lesion, had a significantly higher diagnostic yield (105/121, 87%) than when the probe was located adjacent to it (8/19, 42%). Diagnostic yield from EBUS-GS in lesions ≤10 mm (16/21, 76%), 10< ≤ 15 mm (19/25, 76%, p=0.99, χ2), 15< ≤20 mm (24/35, 69%, p=0.41, χ2), and 20< ≤30 mm (33/43, 77%, p=0.96, χ2) were similar, demonstrating the efficacy of EBUS-GS even in lesions ≤10 mm in diameter.
key words: Endobronchial ultrasonography (EBUS), Peripheral pulmonary lesion, Guide sheath

JJLC 48 (4): 318-326, 2008

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