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Vol.48 No.6 contents Japanese/English

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Article in Japanese

- Case Report -

A Case of Non-small Cell Lung Cancer with Paranasal Sinus Metastases

Asao Sakai1,3, Keiichi Iwasa1, Yoshinobu Maeda2, Hideharu Kimura3, Kazuo Kasahara3, Masaki Fujimura3
1Department of Respiratory Medicine, 2Department of Surgical Pathology, Toyama Red Cross Hospital, Japan, 3Department of Respiratory Medicine, Cellular Transplantation Biology, Graduate School of Medicine, Kanazawa University, Japan

Background. Even though the head and neck are common metastatic sites in lung cancer patients, paranasal metastases are rare. We report a patient with lung cancer who had paranasal sinus metastases. Case. A 56-year-old man with lung cancer presented with nasal hemorrhage 1.5 years after the initiation of chemotherapy. On CT, mass shadows were seen in bilateral frontal sinuses, maxillary antra, the left ethmoidal sinus, the sphenoidal sinus, and the nasal cavity. Biopsies of the lesion in the nasal cavity showed adenocarcinoma, confirming that the lesions in the paranasal sinuses were lung cancer metastases. The cranial MRI done at the time of the first admission was reviewed, and a small nodule was found in left ethmoidal sinus. Conclusion. Paranasal sinus metastases are found in a patient with NSCLC who don't have symptoms related to the paranasal sites. Paranasal sites should be carefully evaluated in patients with advanced NSCLC.
key words: Paranasal metastasis, Lung cancer

Received: December 26, 2007
Accepted: August 12, 2008

JJLC 48 (6): 715-720, 2008

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