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Vol.49 No.4 contents Japanese/English

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Article in Japanese

- Case Report -

A Case of Benign Metastasizing Leiomyoma of the Lung Complicated with Primary Lung Cancer

Yoshihiko Tsunoda1, Koichi Tanaka1, Masaru Hagiwara2, Masaki Mori3, Tsukasa Saito3, Satoshi Kaneko3
1Department of Surgery, Sapporo-Kosei General Hospital, Japan, 2Department of Thoracic Surgery, Niizashiki Chuo General Hospital, Japan, 3Department of Respiratory Medicine, Sapporo-Kosei General Hospital, Japan

Background. Benign metastasizing leiomyoma (BML) is a rare disease among the benign leiomyomas occurring in the lung. All of the cases had previously uterine leiomyoma, which was histologically benign. We present a case of BML complicating primary lung cancer. Case. A 51-year-old woman had undergone total abdominal hysterectomy under the diagnosis of uterine leiomyoma at the age of 38 years. She was found to have an abnormal shadow on chest X-ray, and was then referred to our hospital. Chest CT scan revealed an ill-defined solid tumor, which measured 1.9×1.8 cm in size and was located in the left S10, and a total of 19 smoothly marginated nodules, 3 to 7 mm in diameter, were also found in the bilateral lung fields. We performed thoracoscopic-assisted lower lung partial resections in order to make a definitive diagnosis and for treatment strategy decision. The tumor in the left S10 was a primary lung adenocarcinoma, while the small nodular lesions were determined to be BML. We subsequently performed left lower lobectomy and lymph node dissection for radical treatment of lung cancer. No additional therapy was done and, the patient remains asymptomatic without new growth of the lung tumors nor recurrence of the lung cancer 12 months after the lobectomy. Conclusion. To date, there are 123 cases of BML in the literature. This is the first case report of primary lung cancer complicating BML.
key words: Pulmonary leiomyoma, Benign metastasizing leiomyoma, Lung cancer, Uterine leiomyoma

Received: February 2, 2009
Accepted: March 16, 2009

JJLC 49 (4): 445-449, 2009

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