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Vol.50 No.1 contents | Japanese/English |
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- Case Report -
A Case of Combined Pulmonary Small Cell Carcinoma, Osteosarcoma and Squamous Cell Carcinoma
Kousuke Hamai1,3, Hiromi Egawa1,2, Aya Sugiyama1,3, Hiroshi Murai1,3, Mayumi Kaneko21Department of Internal Medicine, 2Department of Pathology, Hiroshima City Asa Hospital, Japan, 3Department of Molecular and Internal Medicine, Hiroshima University, Japan
Background. Pulmonary small cell carcinoma sometimes contains other histological tumor elements. In most cases, the other elements are squamous cell carcinoma or adenocarcinoma. It is known, however, that in very rare cases small cell carcinoma can be accompanied by sarcomatous elements. Case. A 54-year-old man presented with cough and dyspnea on exertion, and lung cancer was suspected after chest X-rays. His dyspnea worsened, starting the day prior to admission, and he required artificial respiration management by the day of hospitalization. We conducted bronchofiberscopy by intubation, resulting in a diagnosis of small cell carcinoma. Although chemotherapy was administered, the patient died 14 days after admission. Based on the autopsy results, pulmonary small cell carcinoma combined with limited osteosarcoma and squamous cell carcinoma was diagnosed. Only extremely rarely is pulmonary small cell carcinoma accompanied by sarcomatous elements. Conclusion. We report a case of combined pulmonary small cell carcinoma, osteosarcoma and squamous cell carcinoma.
key words: Combined small cell carcinoma, Osteosarcoma, Chemotherapy, Artificial ventilation, Oncological emergency
Received: July 8, 2008
Accepted: August 24, 2009
JJLC 50 (1): 15-20, 2010
