 |
Vol.50 No.1 contents | Japanese/English |
 | Full Text of PDF (1033K) Article in Japanese |
- Case Report -
A Case of Primary Synovial Sarcoma of the Lung
Kenya Yoshida1, Masashi Yamamoto1, Koichiro Shima1, Toshinobu Nakamura1, Harunori Nakashima1, Yoshihiro Takeyama11Department of Respiratory Medicine, Nagoya Ekisaikai Hospital, Japan
Background. Primary synovial sarcoma of the lung is an extremely rare neoplasm. Case. When a 61-year-old man visited our hospital for follow-up of angina pectoris, a nodule was found in the left middle lung field on the chest X-ray film. Uptake was seen only in the pulmonary nodule on fluoro-deoxyglucose (FDG)-PET CT, with no uptake in other regions. Because this case was considered to be sarcoma with limited lung resection, a left upper lobectomy was performed. Histologically, a dense proliferation of spindle cells was seen. These cells stained positively for bcl-2 protein and CD99 and partially for vimentin and S-100 protein. SYT-SSX-1 fusion gene transcripts were detected by reverse transcription polymerase chain reaction (RT-PCR). There was no evidence of tumor of the limbs on physical examination. As a result, we diagnosed primary synovial sarcoma of the lung. Conclusion. We experienced a case of primary synovial sarcoma of the lung.
key words: Synovial sarcoma, SYT-SSX fusion gene, Reverse transcription polymerase chain reaction (RT-PCR), Lung, Immunohistochemistry
Received: April 17, 2009
Accepted: December 8, 2009
JJLC 50 (1): 58-62, 2010
