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Vol.50 No.2 contents | Japanese/English |
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- Case Report -
A Case of Pulmonary Carcinosarcoma After Surgery for Breast Cancer
Seijiro Sato1, Toru Shirato1, Ken-ichi Togashi1, Kazuhiro Sato21Department of Thoracic Surgery, 2Department of Respiratory Medicine, Japanese Red Cross Nagaoka Hospital, Japan
Background. Carcinosarcoma of the lung is a rare malignant tumor. As no effective treatment other than surgery has been established, its outcome is often poor. Case. The patient was a 65-year-old woman who had undergone atypical mastectomy to treat right breast cancer at the age of 61. After 47 months, a mass of about 3 cm was detected in the S3 region of the right lung on chest CT during a follow-up examination. Bronchoscopic findings suggested primary adenocarcinoma of the lung, and upper and middle lobectomy of the right lung and ND2a were performed. Histopathological examination indicated carcinosarcoma of the lung, in which poorly differentiated adenocarcinoma and chondrosarcoma were mixed, and which was T2N1M0 p-stage IIB. After surgery, adjuvant chemotherapy using gemcitabine was given. Twenty-five months after this surgery, breast cancer metastasis to the femur, and images of multiple masses in bilateral lungs were noted. The lung masses were also considered to be breast cancer metastasis, and chemotherapy using TS-1®, carboplatin, paclitaxel, and docetaxel was given, but the patient developed respiratory insufficiency and died 42 months after surgery for carcinosarcoma of the lung. Conclusion. We report a patient who developed carcinosarcoma of the lung after surgery for breast cancer.
key words: Pulmonary carcinosarcoma, Adenocarcinoma, Chondrosarcoma, Breast cancer, Immunohistochemical finding
Received: August 28, 2009
Accepted: February 2, 2010
JJLC 50 (2): 172-177, 2010
