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Vol.52 No.1 contents | Japanese/English |
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- Case Report -
A Case of Pulmonary Carcinosarcoma with Calcification in the Tumor Observed on Computed Tomography
Sayuri Boh1, Ryoichi Kamimura1, Masaru Tsujimoto2, Eikichi Okada3, Akira Watanabe41Department of Radiology, 2Department of Thoracic and Vascular Surgery, 3Department of Pathology, 4Department of Internal Medicine, Takaoka City Hospital, Japan
Background. Pulmonary carcinosarcoma is rare lung tumor composed of carcinomatous and heterotopic sarcomatous components, but there are few reports on the imaging diagnosis of pulmonary carcinosarcoma. Case. A 66-year-old man was admitted to our hospital with right shoulder pain and dyspnea. A chest X-ray film revealed a large quantity of right pleural effusion and chest computed tomography (CT) showed right pleural effusion and a cavitated giant tumor in the right lung field. Cancer cells were detected in his pleural effusion and we made a diagnosis of lung cancer (cT3N0M1a, stage IV). However, despite chemotherapy (CBDCA+GEM), the tumor progressed and the development of calcification in the tumor was observed on a CT scan 6 months after his first presentation. The patient subsequently died 7 months after presentation. The pathological findings of an autopsy specimen revealed the tumor to be composed of squamous cell carcinomatous components, fibrosarcomatous components, chondrosarcomatous components, osteosarcomatous components and rhabdomyosarcomatous components. We made a final diagnosis of pulmonary carcinosarcoma. We observed an osteosarcomatous component with neoplastic osteoids and ossification which showed as areas of calcification on a CT scan, corresponding to neoplastic bones of osteosarcomatous components. Conclusion. We present a case of a pulmonary carcinosarcoma with development of calcification in the tumor. The osteosarcomatous components in the carcinosarcoma were observed as areas of calcification on CT.
key words: Pulmonary carcinosarcoma, Osteosarcoma, Chondrosarcoma, Calcification, CT
Received: August 1, 2011
Accepted: November 16, 2011
JJLC 52 (1): 27-31, 2012
