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Vol.52 No.3 contents Japanese/English

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Article in Japanese

- Case Report -

Successful Salvage Surgery of a Locally Recurrent Squamous Cell Lung Cancer Under Cardiopulmonary Bypass After Effective Chemoradiation

Hironobu Shiota1, Tomohisa Yasukawa1, Ayako Hirai1, Masako Chiyo1, Toshikazu Yusa1, Yukio Saito2
1Department of General Thoracic Surgery, Chiba Rosai Hospital, Japan, 2Department of General Thoracic Surgery, Chiba Medical Center, Japan

Background. The safety and efficacy of salvage surgery of locally advanced non-small cell lung cancer (LA-NSCLC) with local recurrence after chemoradiotherapy is not established. However, a small number of patients were treated with salvage surgery according to our experience. Case. A 58-year-old man visited his local hospital complaining of cough. A chest X-ray revealed a right upper mediastinal mass and a left hilar mass. He was referred to our hospital and primary squamous cell carcinoma of the left upper lobe was diagnosed. The staging was T2aN3M0 (IIIB). He received concurrent chemoradiotherapy consisting of 6 cycles of carboplatin and paclitaxel with conventional radiation therapy of 60 Gy. Two and half years later, progression of primary lung tumor was observed. During the second line treatment with gemcitabine and vinorelbine, massive hemoptysis required emergency admission. CT showed a tumor with a cavity adjoining the left pulmonary artery. To prevent recurrence of hemoptysis, he received complete left pneumonectomy with a patch plasty of the pulmonary artery, salvage surgery under cardiopulmonary bypass. He is disease-free after more than 5 years. Conclusion. Although the role of salvage surgery for locoregional recurrence of LA-NSCLC after effective chemoradiotherapy needs further investigations, salvage surgery can offer a potential for long-term survival in some cases.
key words: Locally advanced non-small cell lung cancer, Salvage surgery, Chemoradiotherapy, Cardiopulmonary bypass

Received: January 31, 2012
Accepted: April 27, 2012

JJLC 52 (3): 300-304, 2012

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