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Vol.52 No.4 contents | Japanese/English |
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- Case Report -
A Case of Pulmonary Aspergillosis in Vacuous Lung Adenocarcinoma
Makiko Sugiura1, Haruhiro Saito1, Hiroyuki Ito2, Tomoyuki Yokose3, Haruhiko Nakayama2, Kouzo Yamada11Department of Respiratory Medicine, 2Department of Thoracic Surgery, 3Department of Pathology, Kanagawa Cancer Center, Japan
Background. Pulmonary aspergillosis in lung cancer rarely occurs simultaneously, although a few cases have been reported in Japan. This report concerns a case of vacuous lung cancer, in which Aspergillus fungal components was detected in the resected specimen. Case. The chest X-ray of a 76-year-old man revealed a vacuous round tumor in the lower lobe of his left lung. The thin-section CT image revealed thick cavity walls, but the thickness of the walls was irregular and partitioned. A lower lobectomy of the left lung was performed. The histological diagnosis of the tumor unveiled poorly differentiated adenocarcinoma (stage IIB, pT3N0M0), which included Aspergillus fungal components. Conclusion. Lung cancer involving aspergillosis is rare and cavities are detected in many of such cases. In this case, we concluded that the Aspergillus infections were can be caused by local immunodeficiency, induced by lung cancer. The cavities in this case were formed because of several factors.
key words: Pulmonary aspergillosis, Cavity, Adenocarcinoma, Lung cancer
Received: December 9, 2011
Accepted: June 26, 2012
JJLC 52 (4): 414-419, 2012
