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Vol.55 No.1 contents Japanese/English

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Article in Japanese

- Case Report -

Gastric Perforation Occurring Twice During Chemotherapy for Lung Adenocarcinoma Metastasis

Ayano Nakazono1, Haruhiro Saito1, Tomoyuki Yokose2, Kouzo Yamada1
1Department of Thoracic Oncology, 2Department of Pathology, Kanagawa Cancer Center, Japan

Background. Gastric metastasis of primary lung cancer is relatively rare. However, reports of this condition have increased in recent years. Gastric metastatic lesions have the potential to influence the course of treatment and quality of life. Hence, physicians must appropriately examine the treatment options on a case-by-case basis. Case Study. A 65-year-old male diagnosed with adenocarcinoma of the right superior lobe underwent resection of the right superior lobe. One year and four months after the surgery, he was diagnosed with a gastric metastatic tumor related to lung carcinoma. He was started on systemic chemotherapy and subsequently suffered from gastric perforation twice during the course of treatment. The first perforation was treated non-surgically, while the second was treated surgically. Conclusion. In Japan, there are approximately 30 previous reports of cases of comorbid gastric metastasis in which the patient underwent surgery. Among these cases, almost all of the patients exhibited severe clinical symptoms. Identifying asymptomatic cases and determining the timing and indications for surgery for metastatic lesions are difficult problems that must be discussed adequately.
key words: Lung adenocarcinoma, Gastric metastasis, Gastric perforation

Received: July 4, 2014
Accepted: January 16, 2015

JJLC 55 (1): 24-29, 2015

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