 |
Vol.56 No.1 contents | Japanese/English |
 | Full Text of PDF (827K) Article in Japanese |
- Case Report -
A Case of Primay Mixed-type Germ Cell Tumor of the Mediastinum with a Solitary Rib Metastasis in an Elderly Patient
Fumihiro Ishibashi1, Yuuki Shiina1, Yukiko Matsui1, Yasumitsu Moriya1, Toshihiko Iizasa11Division of Thoracic Diseases, Chiba Cancer Center, Japan
Background. Primary germ cell tumors of the mediastinum are rare. Case. A 68-year-old man presented to our department with a chest CT revealing an anterior mediastinal mass and tumor of the left 6th rib. Although we suspected a rib metastasis from a thymoma or thymic cancer, a biopsy of the 6th rib tumor was non-diagnostic and the mediastinal tumor could not be biopsied. The patient therefore underwent video-assisted thoracoscopic surgery for diagnostic purposes and to determine a treatment strategy. The examination of an intra-operative frozen section of the left 6th rib tumor revealed a malignant tumor. The mediastinal tumor was removed and an en bloc partial resection of the left upper lobe of the lung was performed. The mediastinal tumor was diagnosed as a primary mixed-type germ cell tumor consisting of a seminoma, a mature teratoma, and an embryonal carcinoma; the rib metastasis originated from a component of the mediastinal tumor. Four courses of chemotherapy (cisplatin, etoposide, and ifosfamide) were administered. Conclusion. Primary germ cell tumors of the mediastinum are primarily found in young men. There are few reports of their occurrence in elderly patients. We herein reported a rare clinical event involving a primary mixed-type germ cell tumor of the mediastinum with an unusual bone metastasis.
key words: Mediastinal tumor, Mixed-type germ cell tumor, Solitary metastasis, Bone metastasis
Received: September 17, 2015
Accepted: December 8, 2015
JJLC 56 (1): 27-32, 2016
