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Vol.56 No.7 contents | Japanese/English |
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- Case Report -
Two Cases of Pulmonary Epithelioid Hemangioendothelioma
So Ishii1, Isao Matsumoto1, Munehisa Takata1, Masaya Tamura1, Daisuke Saito1, Hirofumi Takemura11Department of Thoracic, Cardiovascular and General Surgery, Kanazawa University, Japan
Background. Epithelioid hemangioendothelioma is an extremely rare non-epithelial tumor originating from the vascular endothelial cells that arises in organs such as the lungs and liver. We report two cases of epithelioid hemangioendothelioma in which it was difficult to make a preoperative diagnosis. Case 1. A 67-year-old male patient was found to have an abnormal shadow on a chest X-ray during a health-checkup, was referred to our department. Chest computed tomography (CT) showed a nodule of 1.5 cm in diameter at segment 1+2 of the left lung. The patient underwent left upper lobectomy and partial resection of segment 6 of the left lung with ND2a-1 lymph node dissection for suspected left lung cancer. The frozen section diagnosis was papillary adenocarcinoma. Following a postoperative pathological examination, the patient was diagnosed with epithelioid hemangioendothelioma. Case 2. A 64-year-old woman presented with coughing symptoms. A chest X-ray and CT showed multiple nodules, and the patient was referred to our department for diagnostic purposes. Abdominal magnetic resonance imaging (MRI) also showed multiple hepatic nodules. The patient underwent partial resection of the right middle and lower lobe of the lung to allow for the definite diagnosis of the abnormal shadow. Epithelioid hemangioendothelioma was diagnosed based on the pathological findings. Conclusions. We encountered two cases of epithelioid hemangioendothelioma in which it was difficult to make a preoperative diagnosis. A surgical biopsy and immunohistochemistry are useful for making a definitive diagnosis in cases of epithelioid hemangioendothelioma.
key words: Epithelioid hemangioendothelioma, Malignant lung tumor
Received: May 20, 2016
Accepted: August 7, 2016
JJLC 56 (7): 1028-1033, 2016
