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- Case Report -

A Case of Chordoma Detected as a Mediastinal Tumor

Shugo Takahashi¹, Masafumi Mitsui¹, Shota Izukawa², Hidenobu Iwai¹, Satoshi Fujishima¹, Nobuhisa Yajima³, Kazuhiro Imai⁴, Yoshihiro Minamiya^4
1Department of Thoracic Surgery, Hachinohe City Hospital, Japan, ²Department of Surgery, Towada City Central Hospital, Japan, ³Department of Clinical Laboratory, Hachinohe City Hospital, Japan, ⁴Department of Thoracic Surgery, Akita University Graduate School of Medicine, Japan

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Background. Chordoma, a rare malignant tumor that originates from primitive notochord remnants, commonly affects the sacrum, skull base, and mobile spine. However, chordomas may rarely present as paravertebral mediastinal tumors. Case. A 54-year-old man at his annual checkup underwent chest radiography, which revealed an extra-pleural nodule in the right upper lung field. Chest computed tomography (CT) revealed a right paravertebral tumor at the upper mediastinum. We clinically diagnosed the mass as a benign neurogenic tumor, and it was removed surgically. A histopathological examination showed large vacuolated cells arranged in sheets and myxoma-like tissues characteristic of chordoma. We pathologically diagnosed the tumor as chordoma based on the brachyury-positive status. No subsequent therapies were administered, and no recurrence was observed at the six-month follow-up. Conclusion. We herein report a case of mediastinal chordoma treated with surgical resection.
key words: Chordoma, Malignant bone tumor, Mediastinal tumor

Received: March 7, 2022
Accepted: April 18, 2022

JJLC 62 (4): 317-322, 2022