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Vol.62 No.4 contents Japanese/English

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Article in Japanese

- Case Report -

A Case of Thoracic SMARCA4-deficient Undifferentiated Tumor Diagnosed Definitely by Pleural Cryobiopsy during Semiflexible Thoracoscopy

Juri Tsuchimoto1,2, Tatsuru Ishikawa2, Yuta Koshino2, Takumi Ikeda2, Kenta Kobashi2, Kento Yasuda2, Takayuki Nagao1,2, Yuichiro Asai2, Yuki Mori2, Hirofumi Chiba2
1Department of Respiratory Medicine, Muroran City General Hospital, Japan, 2Department of Respiratory Medicine and Allergology, Sapporo Medical University, School of Medicine, Japan

Background. Pleural biopsy during semiflexible thoracoscopy is useful for the diagnosis of pleural effusion. However, we sometimes experience cases in which the tumor is difficult to grasp with a flexible forceps because of the properties of the pleura. Case. The patient was a 51-year-old man with idiopathic interstitial pneumonia, who was found to have left pleural effusion. We attempted to perform pleural biopsy using a flexible forceps during semiflexible thoracoscopy; however, it was impossible because it was fibrous and hard lesion. Therefore, we performed thoracoscopic pleural biopsy with a cryoprobe. Cryobiopsy enabled us to obtain a specimen. A thoracic SMARCA4-deficient undifferentiated tumor was diagnosed based on the pathological findings. Conclusion. Pleural cryobiopsy during semiflexible thoracoscopy may be useful for the diagnosis of patients with an extensive fibrous pleura, in which the tumor is difficult to grasp with a flexible forceps.
key words: Cryobiopsy, Semiflexible thoracoscopy, Pleural biopsy, Thoracic SMARCA4-deficient undifferentiated tumor, Pleural effusion

Received: April 4, 2022
Accepted: May 11, 2022

JJLC 62 (4): 345-349, 2022

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