![タイトル](img/title07_e.jpg)
![]() |
Vol.64 No.1 contents | Japanese/English |
![]() | Full Text of PDF (1167K) Article in Japanese |
- Case Report -
A Case of Lung Adenocarcinoma in Which Arthritic Pain and Edema Associated with RS3PE Syndrome Significantly Improved After Surgery
Shuta Kimura1, Kazuki Hayasaka1, Tomohiro Fujita1, Syunsuke Eba1, Hidekachi Kurotaki2, Nobuyuki Sato11Department of Thoracic Surgery, 2Department of Pathology, Aomori Prefectural Central Hospital, Japan
Background. Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome is a condition characterized by symmetrical synovitis and pitting edema in the extremities. It is often associated with malignant tumors. While there have been several reported cases of RS3PE syndrome associated with lung cancer, few have described the extent or nature of the improvement in RS3PE syndrome symptoms following treatment for lung cancer. Case. A 63-year-old man presented with bilateral peripheral edema and pain and was diagnosed with RS3PE syndrome. Although he was initially independent in his activities of daily living (ADL), he had been experiencing poor grip strength and difficulty walking due to arthralgia. A CT scan conducted to screen for malignant tumors revealed a mass in the right upper lobe of the lung that was suspected to be lung cancer. The patient underwent surgery to remove the lung adenocarcinoma. A pathological examination revealed that the cancer was stage IIB, with no lymph node involvement or metastasis. The edema improved on the day after surgery, and the arthralgia improved on the third postoperative day. On the eighth postoperative day, the patient's grip strength and six-minute walking distance had remarkably improved in comparison to the pre-operative measurements. His ADL had also improved. Conclusion. In cases of RS3PE syndrome associated with surgically resectable lung cancer, surgery may improve the symptoms of RS3PE syndrome.
key words: RS3PE syndrome, Lung cancer, Paraneoplastic syndrome, Surgery, VEGF
Received: June 28, 2023
Accepted: November 19, 2023
JJLC 64 (1): 39-44, 2024