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Vol.57 No.4 contents Japanese/English

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Article in Japanese

- Case Report -

A Case of Pseudomesotheliomatous Carcinoma of the Lung Diagnosed by Thoracoscopy Under Local Anesthesia

Kazushi Yamairi1, Yasuhiro Takagi1, Keisuke Kureya1, Yoshimi Sugama1, Satoshi Shiraishi1
1Department of Respiratory Medicine, Osaka City Juso Hospital, Japan

Background. Pseudomesotheliomatous carcinoma of the lung (PMCL) is a disease that resembles pleural mesothelioma. PMCL is characterized by diffuse invasion along the visceral and parietal pleura, and is histologically defined as peripheral lung cancer. Case. A 62-year-old man with right chest pain was referred to our hospital for right pleural effusion. Chest computed tomography revealed right pleural thickening, but no abnormal lung findings. A biopsy specimen obtained during thoracoscopy under local anesthesia showed adenocarcinoma, which was consistent with lung cancer (clinical stage; TXN0M1a: IV). Chemotherapy with carboplatin, pemetrexed, and bevacizumab was initiated. The patient completed 3 cycles of chemotherapy, which suppressed the progression of the disease, while maintaining his performance status. Nevertheless, the lung cancer subsequently progressed. He chose supportive care, and ultimately died 7 months after the diagnosis. Conclusion. We reported a case of PMCL that was diagnosed by thoracoscopy under local anesthesia. PMCL should be included in the differential diagnosis in cases with malignant pleural effusion with no primary tumor in the lung. It is important to make an appropriate diagnosis.
key words: Pseudomesotheliomatous carcinoma of the lung, Pleural mesothelioma, Thoracoscopy under local anesthesia, Immunohistochemical examination

Received: December 21, 2016
Accepted: April 12, 2017

JJLC 57 (4): 286-291, 2017

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