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Vol.58 No.3 contents | Japanese/English |
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- Case Report -
A Case of Granular Cell Tumor with Lymph Node Infiltration
Ryo Ohtsuka1, Kazuhiro Ueda1, Toshiki Tanaka1, Junichi Murakami1, Atsunori Oga2, Kimikazu Hamano11Division of Chest Surgery, Department of Surgery and Clinical Science, 2Department of Molecular Pathology, Yamaguchi University Graduate School of Medicine, Japan
Background. Although granular cell tumor (GCT) is mainly a benign disease, local recurrence often occurs after resection. However, the causes of recurrence are unclear. Case. A 65-year-old woman was referred to our hospital for the further examination of a pulmonary nodule in her right upper lobe. Chest computed tomography showed a 25-mm solid nodule in the right S2. Bronchoscopy showed white nodules at the right B2, and a biopsy was performed. S-100 protein, NSE, and CD68 were positively stained by immunohistochemistry, and the diagnosis was GCT. Thoracoscopic right upper lobectomy was performed because the tumor was located close to the hilum. The findings on a histological examination were compatible with benign GCT, but it had infiltrated to the adjacent lymph nodes. Conclusion. Lymph node infiltration may be a cause of local recurrence of GCT. A sufficient safety margin is the most important factor for preventing local recurrence after surgical resection. Thus, anatomical lung resection should be considered for this disease.
key words: Granular cell tumor, Lymph node infiltration
Received: January 4, 2018
Accepted: March 9, 2018
JJLC 58 (3): 221-226, 2018
