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Vol.58 No.5 contents | Japanese/English |
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- Original Article -
Clinical Implications of Margin Cytology of Sublobar Resection for Lung Cancer
Noriyoshi Sawabata1, 2, Takeshi Kawaguchi1, Motoaki Yasukawa1, Norikazu Kawai1, Takeru Hyakutake3, Shigeki Taniguchi11Department of Thoracic and Cardiovascular Surgery, Nara Medical University School of Medicine, Japan, 2Division of Respiratory Surgery, Hoshigaoka Medical Center, Japan, 3Division of Respiratory Surgery, Takai Hospital, Japan
Objective. The importance of obtaining a sufficient margin distance in sublobar lung resection of clinical stage I lung cancer is widely recognized. However, the clinical implications regarding cytology of the resected lung margin remain unclear. We therefore conducted a clinical investigation of this issue. Methods. An anonymous database was created and analyzed by referring to the medical records of patients who underwent sublobar lung resection for clinical stage I lung cancer. Results. Among patients who underwent sublobar lung resection (11 segmentectomies and 22 wedge resections), the results of margin cytology were negative in 24 cases, suspicious in 6 cases and positive in 3 cases. The hazard ratio for positive margin cytology, compared with a negative result, with recurrence as the endpoint, was 59.5 (95% confidence interval: 5.6-630.4), and a positive finding was an independent indicator of relapse of margin distance. Conclusion. These findings suggest that margin cytology is a useful parameter among patients with clinical stage I lung cancer who have undergone sublobar lung resection.
key words: Lung cancer, Sublobar resection, Margin distance, Margin cytology
Received: May 15, 2018
Accepted: July 24, 2018
JJLC 58 (5): 338-343, 2018
