 |
Vol.59 No.1 contents | Japanese/English |
 | Full Text of PDF (1080K) Article in Japanese |
- Case Report -
An Autopsy Case of Giant Benign Solitary Fibrous Tumor of the Pleura That Became Lethal
Takehiro Tsuchiya1, Atsushi Sano1, Akane Oku2, Tsutomu Fukuda21Department of Thoracic Surgery, 2Department of Respiratory Medicine, Chigasaki Municipal Hospital, Japan
Background. Solitary fibrous tumors of the pleura (SFTP) are uncommon pleural tumors derived from mesenchymal cells. The mainstay of treatment for SFTP is surgical resection. Our patient declined a detailed evaluation and treatment of a giant intrathoracic tumor. We therefore observed the natural history of the tumor until the patient's death. Case. A 69-year-old woman with dyspnea was referred to our hospital for treatment. Although computed tomography showed a giant intrathoracic tumor occupying the right hemithorax, she declined a detailed evaluation and treatment. She was lost to follow-up until she presented to the hospital again, often with dyspnea. Over time, the tumor increased in size and began to compress the right lung and heart. At 82 years of age, she suffered from severe dyspnea and presented to our hospital. She died of respiratory failure. An autopsy revealed that the tumor, which was compressing the right lung and heart, arose from the visceral pleura. A histological examination revealed that it was a uniform spindle cell tumor. In addition, immunohistochemical staining revealed that the tumor cells were positive for CD34 and STAT6. As a result, the tumor was diagnosed as SFTP. Conclusion. The clinical course of SFTP is rarely observed. Although SFTP is considered a histologically benign tumor, its growth might lead to death due to compression of the heart and lungs.
key words: Solitary fibrous tumor, Giant tumor, Pleural tumor, Autopsy, Clinical course
Received: September 13, 2018
Accepted: December 6, 2018
JJLC 59 (1): 82-87, 2019
