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Vol.59 No.3 contents | Japanese/English |
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- Case Report -
A Case of Adenocarcinoma of the Lung with Garcin Syndrome Presenting with Earache and Facial Paralysis During Chemotherapy
Takashi Yamane11Department of Respiratory Medicine, Kochi Health Sciences Center, Japan
Background. Garcin syndrome is characterized by the presence of unilateral palsies of the cranial nerves, no sensory or motor long tract disturbance, no intracranial hypertension, and an osteoclastic lesion in the skull base. We herein report a case of adenocarcinoma of the lung with Garcin syndrome that was difficult to diagnose at the appearance of earache and facial paralysis during chemotherapy. Case. A 54-year-old man referred to our hospital because of a lung tumor with bone metastasis presented with back pain. He was diagnosed with adenocarcinoma of the lung, cT1bN2M1b, Stage IVA. Palliative radiation therapy relieved his back pain due to lumber vertebral bone metastasis, and chemotherapy was administered. Fourteen months after the diagnosis of lung cancer, left earache and facial paralysis appeared. Brain magnetic resonance imaging (MRI) with post-gadolinium imaging did not show any abnormality, so we clinically diagnosed him with Ramsay Hunt syndrome. The administration of valaciclovir and steroid slightly improved the symptoms. Two months later, left-side paralysis of the recurrent nerve and glossopharyngeal nerve appeared, and brain MRI with post-gadolinium imaging revealed an osteoclastic lesion at the skull base. Conclusion. It is important to consider bone metastasis at the skull base in patients with lung cancer who present with earache and facial paralysis.
key words: Lung cancer, Garcin syndrome, Facial paralysis
Received: February 12, 2019
Accepted: April 6, 2019
JJLC 59 (3): 282-286, 2019
