 |
Vol.60 No.1 contents | Japanese/English |
 | Full Text of PDF (2732K) Article in Japanese |
- Case Report -
A Case of Central Squamous Cell Carcinoma with Extensive in situ Spread
Yohei Kawaguchi1, Yosuke Matsuura1, Hironori Ninomiya2, Sakae Okumura1, Yuichi Ishikawa2, Mingyon Mun11Department of Thoracic Surgical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Japan, 2Division of Pathology, Cancer Institute of Japanese Foundation for Cancer Research, Japan
Background. Primary lung squamous cell carcinoma mostly occurs in the central airway; however, the prevalence of peripheral squamous cell carcinoma is increasing. We report a case of centrally located squamous cell carcinoma that could not be recognized preoperatively and which was found to have spread to the peripheral lung field and formed a solitary nodular lesion. Case. The patient was a 77-year-old man, who had received an endoscopic submucosal resection for hypopharyngeal carcinoma, after a solitary small lung nodule was pointed out on chest CT in an annual checkup. This nodule was located in the peripheral area of the right S3. Right upper lobectomy and systematic lymph node dissection were performed. Pathologically, another tumor mass was found at the B3 bronchus root. This was found to be from the intra-bronchial spread of the original tumor to the periphery (S3). The tumor had further spread to the bronchial stump, which resulted in the detection of cancer cells at the surgical margin. Conclusion. In cases of pulmonary squamous cell carcinoma, even if it is peripheral, intra-bronchial spread may be very extensive (e.g., to the surgical stump of central bronchus).
key words: Squamous cell carcinoma, Intraepithelial invasion, Residual carcinoma at the bronchial stump
Received: July 31, 2019
Accepted: October 24, 2019
JJLC 60 (1): 33-37, 2020
