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Vol.60 No.1 contents | Japanese/English |
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- Case Report -
A Case of Primary Pulmonary Classical Hodgkin Lymphoma
Yohei Takumi1, Takashi Karashima1, Miyuki Abe1, Michiyo Miyawaki1, Tsutomu Daa2, Kenji Sugio11Department of Thoracic and Breast Surgery, 2Department of Diagnostic Pathology, Oita University, Japan
Background. Pulmonary Hodgkin lymphoma is a rare tumor, and its preoperative diagnosis is difficult. Case. A 39-year-old woman showed an abnormality on chest radiography during the preoperative examination of appendicitis. Computed tomography (CT) of the chest revealed a pulmonary mass 5 cm in diameter in the left upper lobe that reached the pericardium. Transbronchial biopsies (TBBs) revealed a malignant appearance of unknown histology. Left upper lobectomy and mediastinal lymph node dissection were subsequently performed. Microscopic findings showed malignant cells containing diffuse Hodgkin cell and multinucleated Reed-Sternberg cells. Immunohistochemical findings revealed that the tumor cells were positive for anti-CD30 and anti-CD15 antibody. Therefore, this tumor was diagnosed as classic Hodgkin lymphoma, nodular sclerosis type, with a pulmonary origin, as extrapulmonary disease was not present. Conclusion. It is important to make an accurate diagnosis of pulmonary malignant lymphoma in order to select the proper treatment.
key words: Primary pulmonary classical Hodgkin lymphoma
Received: July 3, 2019
Accepted: November 5, 2019
JJLC 60 (1): 43-47, 2020
