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Vol.60 No.3 contents | Japanese/English |
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- Case Report -
A Case of Macroscopic Complete Resection of Stage IVa Thymoma After Induction Chemotherapy
Shunichi Baba1, Hironori Ishibashi1, Sachiko Imai1, Masashi Kobayashi1, Takumi Akashi2, Kenichi Okubo11Department of Thoracic Surgery, Graduate School of Medical and Dental Sciences, 2Department of Pathology, Tokyo Medical and Dental University, Japan
Background. The optimum treatment strategy for invasive thymomas with pleural dissemination remains unclear. Case. The patient was a 67-year-old woman. She was diagnosed with an anterior mediastinal tumor with left brachiocephalic vein invasion and pleural dissemination based on computed tomography (CT). We diagnosed the tumor as Masaoka clinical stage IVa thymoma by CT-guided biopsy. She received induction chemotherapy with cisplatin, doxorubicin and methylprednisolone (CAMP therapy). After four cycles of CAMP therapy, since CT revealed the remarkable reduction of primary lesion and near disappearance of pleural dissemination, we performed resection of the residual tumor. We completely removed the primary lesion with the left brachiocephalic vein and part of the pericardium, as well as the pleural dissemination via median sternotomy with video-assisted thoracoscopic surgery. At the time of writing, she is alive without recurrence at 17 months after surgery. Conclusion. We experienced a case of macroscopic complete excision of stage IVa thymoma after induction chemotherapy.
key words: Mediastinal tumor, Stage IVa thymoma, Pleural dissemination, Induction chemotherapy, Complete resection
Received: December 24, 2019
Accepted: March 9, 2020
JJLC 60 (3): 181-186, 2020
