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Vol.61 No.3 contents | Japanese/English |
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- Case Report -
A Case of Resected Pulmonary Adenoid Cystic Carcinoma Requiring a Differential Diagnosis from Small-cell Lung Carcinoma
Tatsuya Miyamoto1, Takeshi Mimura1, Atsushi Kagimoto1, Chika Nakashima1, Junichi Zaitsu2, Kazuya Kuraoka2, Mineyo Mito3, Yoshihiro Kitahara3, Kikuo Nakano3, Yukari Endo4, Yoshinori Yamashita11Department of General Thoracic Surgery, 2Department of Diagnostic Pathology, 3Department of Respiratory Medicine, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, Japan, 4Department of Pathology, Tottori University Hospital, Japan
Background. Pulmonary adenoid cystic carcinoma (PACC) is a rare tumor and may be differentially diagnosed as small-cell lung carcinoma (SCLC). We herein report a case of resected PACC that was differentially diagnosed as SCLC. Case. We encountered a 62-year-old non-smoking woman in whom a small nodule on the lower left lobe of the lung was revealed during chest X-ray. Chest computed tomography revealed that a 20-mm diameter nodule had developed in the anterior basal segment of the lung. The tumor was diagnosed as SCLC using a transbronchial biopsy (cT1bN0M0, stage IA2). The patient underwent left lower lobectomy in the department of the hospital. Although a pathological examination revealed that the resected tumor had morphological characteristics similar to SCLC, the results of immunohistochemical staining led to a final diagnosis of differentiated PACC. Conclusion. Although PACC may be differentially diagnosed as SCLC, these cancers require different treatments. If SCLC is clinically unlikely, it is necessary to perform immunohistochemical staining and make a sufficient differentiation from other tumors, such as PACC.
key words: Pulmonary adenoid cystic carcinoma, Small-cell lung carcinoma, Differential diagnosis, Immunohistochemical staining
Received: December 9, 2020
Accepted: February 8, 2021
JJLC 61 (3): 189-194, 2021
