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Vol.61 No.3 contents | Japanese/English |
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- Case Report -
A Case of IgG4-related Disease Composed of a Paravertebral Tumor Alone with Multiple Lung Cancers
Mutsumi Ozasa1, Toyomitsu Sawai1, Yosuke Harada1, Sumako Yoshioka1, Nobuko Matsuo1, Hiroshi Mukae21Department of Respiratory Medicine, Nagasaki Harbor Medical Center, Japan, 2Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan
Background. IgG4-related disease is a fibroinflammatory condition that is capable of affecting multiple organs. There are no previous reports of cases involving a lesion on the paravertebral body alone, and only a few cases involving complication with primary lung cancer have been reported. Case. The patient was a 67-year-old man who had been diagnosed with multiple ground glass nodules (GGNs) on chest CT 6 years previously. During follow-up, a GGN in the right upper lobe increased in size, and lung cancer was suspected. Thus, he presented to our department 2 years previously. Soft tissue tumors around the Th10 vertebral body were recognized at the initial visit to our hospital, and showed a tendency toward enlargement. Right upper lobectomy and a biopsy of the tumor on the paravertebral body revealed that the GGNs were lung adenocarcinoma. A histological examination of the paravertebral tumor revealed IgG4-positive plasma cell infiltration and an increased IgG4 concentration, leading to a diagnosis of IgG4-related disease. Conclusion. This is a valuable case of IgG4-related disease composed of only a paravertebral lesion that co-existed with multiple lung adenocarcinomas.
key words: IgG4-related disease, Lung cancer, Paravertebral tumor
Received: July 14, 2020
Accepted: March 3, 2021
JJLC 61 (3): 213-217, 2021
