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Vol.61 No.3 contents | Japanese/English |
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- Case Report -
A Resected Case of Combined Small Cell Carcinoma Containing Components of Squamous Cell Carcinoma, and Adenocarcinoma
Yui Shimanuki1, Kazutoshi Isobe1, Kyohei Kaburaki1, Akira Iyoda2, Naobumi Tochigi3, Sakae Homma4, Kazuma Kishi11Department of Respiratory Medicine, 2Department of Chest Surgery, 3Department of Surgical Pathology, 4Department of Advanced and Integrated Interstitial Lung Diseases Research, School of Medicine, Toho University, Japan
Background. Combined small cell lung carcinoma is a small cell cancer containing non-small cell lung cancer components, such as adenocarcinoma and/or squamous cell carcinoma. Case. A 61-year-old man with chronic hepatitis B and hepatocellular carcinoma was admitted to our hospital because of a nodule in the right lower lobe that was detected on follow-up CT. His serum carcinoembryonic antigen level was slightly elevated. High-resolution CT revealed a lobulated nodule measuring 10 mm in diameter. Fiberoptic bronchoscopy was nondiagnostic. However, lung cancer was suspected because the nodule increased in size on serial CT. Thoracoscopic right lower lobe resection with mediastinal lymph node resection was performed. A pathological examination of the resected specimen revealed a tumor composed of similar proportions of small cell carcinoma cells, adenocarcinoma cells, and squamous cell carcinoma cells. Conclusion. Most combined small cell carcinomas contain cells of one type of non-small cell carcinoma; however, in the present case, small cell carcinoma, adenocarcinoma, and squamous cell carcinoma cells were distinctively present in similar proportions.
key words: Primary lung cancer, Combined small cell carcinoma, Adenocarcinoma, Squamous cell carcinoma
Received: December 9, 2020
Accepted: March 11, 2021
JJLC 61 (3): 225-229, 2021
