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Vol.61 No.4 contents | Japanese/English |
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- Case Report -
A Case of Extensive-disease Small-cell Lung Carcinoma That Recurred in the Left Adrenal Gland Seven Years After a Long-term Recurrence-free Survival
Yusuke Inui1, Takahiro Ibaraki1, Asuka Okada1, Yuma Watabe1, Katsumasa Koyama1, Tatsuhiro Furuyama1, Masahide Ueda1, Fumitaka Mito1, Hideaki Takenaka1, Sumito Choh11Department of Respiratory Medicine, Saiseikai Suita Hospital, Japan
Background. Extensive-disease small-cell lung carcinoma has a high response rate for the initial treatment; however, most cases recur and are exacerbated in the short term. Case. A 68-year-old man was referred to our hospital because of a right upper lung field mass on a chest X-ray examination. He was diagnosed with small-cell lung carcinoma in the right upper lobe, cT3N2M1b, stage IVB (7th edition of the TNM system for lung cancer). He was treated by combination chemotherapy with cisplatin and irinotecan, and the left cerebellar metastasis disappeared after two courses, with the chest and abdominal lesions disappearing after four courses. He was also treated with whole-brain irradiation because of recurrence of the left cerebellar metastasis on magnetic resonance imaging one month after the final chemotherapy session. He maintained a recurrence-free survival for seven years; however, computed tomography (CT) revealed a mass in the left adrenal gland. The new lesion was pathologically diagnosed as metastasis of small-cell lung carcinoma by laparoscopic left adrenalectomy that was performed for the diagnosis and treatment, although it was considered atypical for extensive-disease small-cell lung carcinoma to recur after a long-term recurrence-free survival. Conclusion. Extensive-disease small-cell lung carcinoma can induce distant metastasis and recurrence after a long-term recurrence-free survival. It is necessary to conduct careful observation of such patients even after a long-term recurrence-free survival is achieved.
key words: Extensive-disease small-cell lung carcinoma, Long-term recurrence-free survival, Late recurrence
Received: March 18, 2021
Accepted: April 30, 2021
JJLC 61 (4): 347-352, 2021
